The 21^st century has witnessed a transformative wave of technological advancements, with artificial intelligence at its forefront. This study explores artificial intelligence in Islamic classical scientific studies in the 21^st century since the development of artificial intelligence has developed broadly. Besides, this study was also exploring the challenges and expectations associated with the development of artificial intelligence. This study used descriptive qualitative study which used instruments as like as depth-interview and documentation. Artificial intelligence has emerged as a powerful tool that holds the potential to revolutionize research methodologies, data analysis, and problem-solving across diverse scientific disciplines. The challenge of artificial intelligence in Islamic classical scientific studies is giving prior knowledge to those who want to get new knowledge. Artificial intelligence can help translate and analyze historical materials, personalize learning, and improve research.  However, the expectations of faculty members were Artificial intelligence and Islamic classical scientific studies would make historical knowledge more accessible, engaging, and relevant or not to 21^st century experts and students in this ever-changing context. Besides, artificial intelligence shouldn't be considered as a replacement for human researchers but rather as a tool to aid and augment.